• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
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    • 专利摘要:
    A composition for topical application comprising natural waxes and their uses. A composition for topical application comprising between 15% to 45% by weight of natural waxes, preferably combining beeswax and lanolin; between 15 to 25% by weight vegetable shortening, preferably kokum butter; and between 15% to 37% by weight of a vegetable oil or a combination of vegetable oils; which also incorporates at least one antibacterial and/or fungicidal agent; essences and vitamin E. The composition is especially designed to prepare a medicine for topical application for the treatment of areas affected by psoriatic plaques or chronic cases of extreme dryness of the skin and for the prevention of pathologies in the skin of a diabetic patient. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2682844A1
    申请号:ES201700268
    申请日:2017-03-21
    公开日:2018-09-21
    发明作者:Ingrid CABALLERO PÉREZ
    申请人:Ingrid CABALLERO PÉREZ；
    IPC主号:
    专利说明:

    DESCRIPTION

    A composition for topical application comprising natural waxes and their uses.

    Technical sector of the invention 5

    The invention relates to a composition comprising waxes of natural origin for topical application and its use for the treatment or prevention of various pathologies.

    Background of the invention 10

    Dry skin or cutaneous xerosis can be mild and characterized by itching and rough skin.

    Occasionally, however, it can become a chronic condition that results in severe cracking and peeling that results in injury, pain and redness.

    Factors such as age, washing the skin with soaps or harsh shampoos too often, as well as exposing the skin to chemicals decrease the amount of natural dermal oils present to keep the skin nourished and can contribute to an increase in dry skin . Environmental factors such as excessive exposure to air conditioning and central heating can also cause excessive dryness, as they reduce humidity in the environment.

    However, even when adequate precautions are taken to mitigate the factors described above, there are patients suffering from extreme chronic dryness.

    Topical ointments, such as anti-inflammatory creams or over-the-counter ointment suppressant ointments, can cause dermal irritation and allergic reactions due to the chemicals contained in these products and do not reverse the 30 effects caused by extreme dryness on numerous occasions of chronic involvement, which occurs especially in heels and elbows.

    An object of the present invention is a new composition capable of reversing the effects that extreme dryness produces on the skin. It is also an objective of the invention a skin repair composition, which reverses the effects produced by other pathologies that affect the quality of the skin, such as psoriasis.

    Another skin involvement is known as the diabetic foot ulcers of the diabetic foot. This appears when there are inadequate blood glucose levels and other factors that frequently occur in people with diabetes (such as high blood pressure or hypercholesterolemia) that cause damage to the vessels and nerves that can cause medium-long term complications.

    Over time, the nerve damage caused by diabetes can cause a loss of sensation in the feet so that a cut, blister or sore may not even be felt. Lesions such as these on the foot can cause ulcers and infections, having identified serious cases that require an amputation.

    Another affectation among diabetic patients are fungi in ones or onychomycosis. It is estimated that one third of diabetics suffer from this condition. Although a mild nail fungus infection can be considered primarily a cosmetic problem for a totally healthy person, the consequences of leaving it untreated can be serious.
    For a person with diabetes because, as has been advanced before, diabetics are more likely than non-diabetic people to suffer serious complications.

    Explanation of the invention.
     5
    The anhydrous composition of the invention is for topical application and is characterized in that it comprises between 15% and 45% by weight of natural waxes; between 15 to 25% by weight of vegetable shortening; and between 15% to 37% by weight of a vegetable oil or a combination of vegetable oils; the composition further comprising at least one antibacterial and / or fungicidal agent; essences and vitamin E. 10

    In a preferred form of the invention, natural waxes comprise beeswax and lanolin, whose presence by weight over the total product is as follows:
    - between 5% and 20% beeswax.
    - between 10% and 25% lanolin. fifteen

    Lanolin is a natural wax produced by the sebaceous glands of some mammals, especially sheep, prepared and applied for various industrial, pharmaceutical and household uses. As for beeswax, white beeswax can be used, which is a virgin wax that is obtained by bleaching the yellow beeswax wax 20 (Apis melifica and Apis ligustica) with oxidizing agents.

    The combination of these ingredients, in the percentages described, with nutritional adjuvants (such as shortening), regenerators, healing and moisturizing protectors (such as vegetable oils) as well as with the properties, among other 25 antioxidants and antibacterials, which Provide the ingredients with less presence leads to a balm that creates a barrier on the skin with significant occlusive properties that has revealed a surprising, very effective response to repair affected skin of extreme dryness despite not having the aqueous phase composition.
     30
    In other proportions, the balm is not presumably effective because it does not create enough barrier on the skin and loses the optimal balance between its occlusive properties and the smoothness, protection, nutrition and repair that characterize the composition according to the invention. Out of the ranges described, the obtainable balm ends up being more like a cream, despite having no aqueous phase, and seriously loses its effectiveness for healing 35 deep cracks, in addition to not acting so immediately.

    Particular embodiments that have been shown to be especially optimal are those whose main components are selected in the following sub-ranges: between 13% and 17% by weight of beeswax; between 18% and 23% by weight of lanolin; between 26% and 40 31% by weight of vegetable shortening; and between 27% and 36% by weight of a combination of vegetable oils.

    Preferably, in one embodiment the antibacterial and / or fungicidal agent comprises zinc oxide or allantoin, and its presence by weight over the total composition is between 1 45% and 1.5%.

    Vegetable butter can be selected from: kokum, cocoa, cupuaçu, shea and avocado or a combination of these. In a preferred embodiment, the vegetable shortening is kokum butter. fifty

    Vegetable oil or oils are preferably selected from: almonds, argan, jojoba, rosehip, raspberry, touloucouna, avocado or camellia.

    According to a particular form of the invention, the composition comprises:

    - 16% by weight of beeswax.
    - 18% by weight of lanolin.
    - 31% by weight of kokum butter. 5
    - 12% by weight of argan oil.
    - 20.50% by weight of almond oil.
    - 1% by weight of zinc oxide.
    - 0.50% by weight of absolute, essence, aroma or essential oil or a combination of these of origin: jasmine, lavender, geranium, mint, tea tree and thyme. 10
    - 1% by weight of vitamin E.

    The composition according to the invention has proved suitable for preparing a medicament for topical application intended for the treatment of areas affected by psoriatic plaques or chronic cases of extreme dry skin. fifteen

    Likewise, the mechanisms of action that have proved efficient for the treatment of areas affected by psoriatic plaques or chronic cases of extreme dry skin have also been shown to prevent pathologies that occur in people with diabetes in the form of infected wounds, loss of sensation and the frequent occurrence of 20 ulcers. For this reason, the use of a composition according to the invention to prepare a topical balm for the prevention of pathologies in the skin of a diabetic patient is disclosed.

    Brief description of the illustrations 25

    Figs. 1a and 1b, show the before and after starting a treatment with the composition according to the invention of a patient affected by extreme dryness in the heels.

    Figs. 2a and 2b, show the before and after starting a treatment with the composition 30 according to the invention in another patient affected by psoriasis at the junction of the instep of one foot and the associated leg shank.

    Detailed description of an embodiment
     35
    For the preparation of a composition according to the invention, one can proceed as follows:

    - Incorporate in a container (A) heated beeswax, chosen as a thickening and stabilizing medium. 40

    - Close the container and heat constantly stirring up to 65 ° C.

    - Once the wax has melted, the components prepared in a heated container (B) must be incorporated on it. The container (A) must be prepared to work at a controlled temperature in a vacuum to avoid aeration of the final product.

    - In the container (B), incorporate lanolin, selected as an emollient and protective element of the skin barrier, and heat up to 45 ° C. Once the lanolin is melted, disperse the zinc oxide, which will perform antibacterial and fungicidal actions, with a high shear mixer. This dispersion must be incorporated under constant agitation, with a helix agitator in the vessel (A) by vacuum.

    - Keep the previous mixture in the container (A), in constant agitation, and cool to a temperature of 30 ° C.

    - Incorporate into the container (A), from the container (B), almond and argan oils, to display soothing, softening and healing effects, previously heated to 5 30 ° C.

    - Incorporate Vitamin E (tocopherol acetate) as an antioxidant and preservative agent, in the container (A), at a temperature of 30 ° C of the previous mixture.
     10
    - Dissolve Vitamin E and, in constant agitation, lower the temperature of the mixture to 25 ° C. Once this temperature is reached, incorporate the aromatic essential oil or oils, such as Sambac jasmine absolute.

    - Pack in constant agitation and let stand for 24. 15

    - Analyze, taking Vitamin E and Zn as tracers.

    The examples in the figures illustrate the effect of a balm with a composition according to the invention in two affected patients of different pathology. The composition applied in these 20 examples consists of:

    - 16% by weight of beeswax purified on pearls (whitish yellow).
    - 18% by weight lanolin; 31% by weight of kokum butter (pure and natural). 25
    - 12% by weight of argan oil (pure, virgin and 1st cold pressure).
    - 20.50% by weight of almond oil (pure, virgin and 1st cold pressure).
    - 1% by weight of zinc oxide; 0.50% by weight of absolute, essence, aroma or essential oil or a combination of these of origin: jasmine, lavender, geranium, mint, tea tree and thyme. 30
    - 1% by weight of vitamin E.

    In both cases, the mode of employment was carried out according to the following guidelines:

    1. Apply the balm on dry and damaged areas. Apply occlusive layer for 7 days. 35

    2. To accelerate the effects of balm, it was recommended to use it at night or at home.

    In the first case, extreme dryness, a substantial improvement in the elasticity and hydration of the skin was observed at 4 days of treatment, as illustrated in Figs. 1a and 1b. 40

    In the second case (psoriasis) there was also a substantial improvement in the elasticity and hydration of the skin and elimination of pruritus on the third day of treatment, as illustrated in Figs. 2a and 2b.
     Four. Five
    Likewise, in diabetic patients who recurrently were affected by fungi in the ones and with diabetic foot, the application of a balm with the composition described above, and of variants within the specified ranges, proved to be at least equally effective in prevention of such effects than current products based on unnatural components. fifty
    权利要求:
    Claims (10)
    [1]

    1. An anhydrous composition for topical application characterized by comprising between 15% and 45% by weight of natural waxes; between 15 to 25% by weight of vegetable shortening; and between 15% to 37% by weight of a vegetable oil or a combination of vegetable oils; 5 which also incorporates at least one antibacterial and / or fungicidal agent; essences and vitamin E.

    [2]
    2. A composition according to claim 1, characterized in that the natural waxes comprise beeswax and lanolin, whose presence by weight over the total product is as follows:
    - between 5% and 20% beeswax.
    - between 10% and 25% lanolin.

    [3]
    3. A composition according to any one of the preceding claims, comprising:
    - between 13% and 17% by weight of beeswax. fifteen
    - between 18% and 23% by weight of lanolin.
    - between 26% and 31% by weight of shortening.
    - between 27% and 36% by weight of a combination of vegetable oils.

    [4]
    4. A composition according to any one of the preceding claims, characterized in that the antibacterial and / or fungicidal agent comprises zinc oxide or alantonia, and because its presence by weight over the total composition is between 1% and 1.5 %.

    [5]
    5. A composition according to any one of the preceding claims, characterized in that the vegetable shortening is selected from: kokum, cocoa, cupuaçu, shea and avocado or a combination thereof.

    [6]
    6. A composition according to the preceding claim, characterized in that the vegetable shortening is kokum butter.
     30
    [7]
    7. A composition according to any one of the preceding claims, characterized in that the vegetable oil or oils are selected from: almonds, argan, jojoba, rosehip, raspberry, touloucouna, avocado or camellia.

    [8]
    8. A composition according to any one of the preceding claims, comprising
    - 16% by weight of beeswax.
    - 18% by weight of lanolin.
    - 31% by weight of kokum butter.
    - 12% by weight of argan oil.
    - 20.50% by weight of almond oil. 40
    - 1% by weight of zinc oxide.
    - 0.50% by weight of absolute, essence, aroma or essential oil or a combination of these of origin: jasmine, lavender, geranium, mint, tea tree and thyme.
    - 1% by weight of vitamin E.
     Four. Five
    [9]
    9. Use of a composition according to any one of the preceding claims to prepare a medicament for topical application intended for the treatment of areas affected by psoriatic plaques or chronic cases of extreme dry skin.

    [10]
    10. Use of a composition according to any one of claims 1 to 8 to prepare a topical application balm for the prevention of pathologies in the skin of a diabetic patient.
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    同族专利:
    公开号 | 公开日
    ES2682844B1|2019-06-26|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US20050058669A1|2003-09-11|2005-03-17|Kimberly-Clark Worldwide, Inc.|Skin care topical ointment|
    US20090068128A1|2007-09-10|2009-03-12|Waddington Tauna A|Scar and rosacea and other skin care treatment composition and method|
    WO2011119794A2|2010-03-26|2011-09-29|The Procter & Gamble Company|Hair removal method and hair removal kit|
    法律状态:
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    优先权:
    申请号 | 申请日 | 专利标题
    ES201700268A|ES2682844B1|2017-03-21|2017-03-21|A composition for topical application comprising natural waxes and their uses|ES201700268A| ES2682844B1|2017-03-21|2017-03-21|A composition for topical application comprising natural waxes and their uses|
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